David H Walker Selected Research

Spotted Fever Group Rickettsiosis (Rickettsialpox)

1/2020	Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections.
1/2017	Rickettsiae as Emerging Infectious Agents.
1/2017	Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium.
11/2013	Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses.
6/2013	Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: evidence of possible mediation by host tRNA-derived small noncoding RNAs.
5/2013	Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the eastern region of Minas Gerais State, Brazil.
9/2009	CD4+ CD25+ Foxp3- T-regulatory cells produce both gamma interferon and interleukin-10 during acute severe murine spotted fever rickettsiosis.
12/2008	Short report: Rickettsia felis outer membrane protein A: a potential tool for diagnosis of patients with flea-borne spotted fever.
8/2007	Prevalence of antibodies against spotted fever group rickettsiae in a rural area of Colombia.
1/2005	Expression of CX3CL1 (fractalkine) in mice with endothelial-target rickettsial infection of the spotted-fever group.

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David H Walker Research Topics

Disease

48	Infections 04/2022 - 02/2002
17	Spotted Fever Group Rickettsiosis (Rickettsialpox) 01/2020 - 06/2003
13	Ehrlichiosis 10/2021 - 05/2003
13	Rickettsia Infections 01/2019 - 06/2003
8	Epidemic Louse-Borne Typhus (Typhus) 01/2020 - 06/2003
5	Fever (Fevers) 05/2016 - 12/2003
5	Septic Shock (Toxic Shock Syndrome) 05/2012 - 01/2004
4	Thrombocytopenia (Thrombopenia) 05/2016 - 09/2003
4	Leukopenia 05/2016 - 09/2003
4	Boutonneuse Fever (Mediterranean Spotted Fever) 01/2016 - 04/2004
4	Communicable Diseases (Infectious Diseases) 02/2012 - 11/2003
3	Scrub Typhus (Typhus, Scrub) 04/2022 - 01/2012
3	Melioidosis 05/2021 - 01/2019
3	Rocky Mountain Spotted Fever (Sao Paulo Typhus) 11/2019 - 07/2004
2	Severe Fever with Thrombocytopenia Syndrome 02/2014 - 11/2013
2	Virus Diseases (Viral Diseases) 02/2014 - 11/2008
2	Disseminated Intravascular Coagulation 01/2013 - 06/2003
2	Necrosis 01/2013 - 03/2006
2	Thrombosis (Thrombus) 07/2012 - 06/2003
2	Compression Fractures (Compression Fracture) 07/2006 - 12/2004
2	Malaria 09/2004 - 03/2004
2	Typhoid Fever (Typhoid) 09/2004 - 03/2004
1	Pneumonia (Pneumonitis) 05/2021
1	Glanders 01/2019
1	Body Weight (Weight, Body) 07/2017
1	Inflammation (Inflammations) 09/2014
1	Viral Hemorrhagic Fevers (Viral Hemorrhagic Fever) 02/2014
1	Bacterial Infections (Bacterial Infection) 12/2013
1	Cytokine Release Syndrome 01/2013
1	Lassa Fever (Fever, Lassa) 10/2012
1	Lymphopenia (Lymphocytopenia) 05/2012
1	Neoplasms (Cancer) 01/2012

Drug/Important Bio-Agent (IBA)

16	AntibodiesIBA 08/2016 - 05/2003
15	VaccinesIBA 04/2022 - 09/2003
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2010 - 06/2003
8	Interleukin-10 (Interleukin 10)IBA 07/2017 - 01/2004
7	Proteins (Proteins, Gene)FDA Link 10/2021 - 05/2003
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 06/2003
6	Interferon-gamma (Interferon, gamma)IBA 12/2011 - 08/2006
5	EnzymesIBA 05/2016 - 02/2007
4	CytokinesIBA 01/2021 - 08/2006
4	Doxycycline (Periostat)FDA LinkGeneric 01/2017 - 02/2003
4	InterferonsIBA 08/2016 - 01/2009
4	AntigensIBA 07/2014 - 05/2003
4	ChemokinesIBA 05/2012 - 10/2003
3	Attenuated VaccinesIBA 01/2019 - 08/2014
3	Interleukin-12 (IL 12)IBA 08/2016 - 02/2004
3	Membrane Proteins (Integral Membrane Proteins)IBA 12/2011 - 04/2004
2	Alanine (L-Alanine)FDA Link 03/2022 - 01/2022
2	RNA (Ribonucleic Acid)IBA 01/2021 - 02/2012
2	Virulence Factors (Pathogenicity Factors)IBA 12/2020 - 06/2003
2	Toll-Like Receptor 4IBA 01/2020 - 08/2008
2	Immunoglobulin G (IgG)IBA 12/2019 - 05/2008
2	Subunit VaccinesIBA 12/2013 - 04/2004
2	LipopolysaccharidesIBA 08/2010 - 04/2004
2	OMPA outer membrane proteinsIBA 12/2008 - 09/2004
2	Chemokine CCL5IBA 09/2007 - 06/2003
2	Glycoproteins (Glycoprotein)IBA 02/2007 - 05/2003
2	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2007 - 10/2005
2	Citrate (si)-Synthase (Synthase, Citrate)IBA 09/2004 - 09/2003
2	Monoclonal AntibodiesIBA 06/2004 - 04/2004
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2003 - 09/2003
1	Interleukin-17 (Interleukin 17)IBA 05/2021
1	Interleukin-1 (Interleukin 1)IBA 01/2021
1	Type VI Secretion SystemsIBA 12/2020
1	InflammasomesIBA 01/2020
1	Tigecycline (Tygacil)FDA Link 11/2019
1	AerosolsIBA 01/2019
1	Untranslated RNA (Noncoding RNA)IBA 01/2019
1	Tyrosine (L-Tyrosine)FDA Link 01/2017
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2017
1	LigandsIBA 01/2017
1	Heparin Lyase (heparin lyase)IBA 01/2017
1	AZD4547IBA 01/2017
1	Interleukin-12 Subunit p40IBA 04/2016
1	Cadherins (E-Cadherin)IBA 01/2016
1	IntegrinsIBA 01/2016
1	Janus KinasesIBA 01/2016
1	Interleukin-18 (Interleukin 18)IBA 01/2016
1	AS 8IBA 01/2016
1	EndotoxinsIBA 01/2016
1	Interleukin-13IBA 09/2014
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2014
1	AngiopoietinsIBA 09/2014
1	Interferon-betaIBA 02/2014
1	MethyltransferasesIBA 01/2014
1	ribosomal protein 29 (RP29)IBA 12/2013
1	3- (5- tert- butylisoxazol- 3- yl)- 2- ((3- chlorophenyl)hydrazono)- 3- oxopropionitrileIBA 11/2013
1	Ribavirin (Virazole)FDA LinkGeneric 11/2013
1	Small Untranslated RNAIBA 06/2013
1	Transfer RNA (tRNA)IBA 06/2013
1	angiogeninIBA 06/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2013
1	Blood Coagulation Factors (Coagulation Factor)IBA 01/2013
1	PerforinIBA 07/2012
1	OligodeoxyribonucleotidesIBA 01/2012
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2012

Therapy/Procedure

5	Therapeutics 01/2017 - 03/2005
2	Vertebroplasty 07/2006 - 12/2004
1	Intraperitoneal Injections 02/2015